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Estrogen Axis and Steroidogenesis Activity Test Estrogenic assay protocols can be adapted to fit your needs and to help you in your decision making process. We can also help you with: Building your testing strategy, Understanding results. Our aim is to help in addressing all of your questions linked to endocrine activity and endocrine disruptors, using our testing tools but also with a large range of expert partners.
Watchfrog Laboratory
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Project-based

Estrogenic assay protocols can be adapted to fit your needs and to help you in your decision making process. We can also help you with: Building your testing strategy, Understanding results. Our aim is to help in addressing all of your questions linked to endocrine activity and endocrine disruptors, using our testing tools but also with a large range of expert partners.

Alternatives to Animal Testing
Customised / Bespoke Services
Thyroid Test Thyroid assay protocols can be adapted to fit your needs and to help you in your decision making process. We can also help you with: Building your testing strategy, Understanding results. Our aim is to help in addressing all of your questions linked to endocrine activity and endocrine disruptors, using our testing tools but also with a large range of expert partners
Watchfrog Laboratory
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Project-based

Thyroid assay protocols can be adapted to fit your needs and to help you in your decision making process. We can also help you with: Building your testing strategy, Understanding results. Our aim is to help in addressing all of your questions linked to endocrine activity and endocrine disruptors, using our testing tools but also with a large range of expert partners

Alternatives to Animal Testing
Customised / Bespoke Services
Androgenic Test Androgen assay protocols can be adapted to fit your needs and to help you in your decision making process. We can also help you with: Building your testing strategy, Understanding results. Our aim is to help in addressing all of your questions linked to endocrine activity and endocrine disruptors, using our testing tools but also with a large range of expert partners.
Watchfrog Laboratory
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Project-based

Androgen assay protocols can be adapted to fit your needs and to help you in your decision making process. We can also help you with: Building your testing strategy, Understanding results. Our aim is to help in addressing all of your questions linked to endocrine activity and endocrine disruptors, using our testing tools but also with a large range of expert partners.

Alternatives to Animal Testing
Customised / Bespoke Services
Alamar Blue Assay Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The Alamar blue assay provides a rapid and sensitive quantitative analysis on cell proliferation and apoptosis. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.
Toxys
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Price Upon Request

Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The Alamar blue assay provides a rapid and sensitive quantitative analysis on cell proliferation and apoptosis. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.

Alternatives to Animal Testing
ToxProfiler MAX Mitotox Assessment Xtension ToxProfiler™ is a unique human in vitro assay that combines seven stable fluorescent reporter genes and can provide an extensive toxicological profile of novel drugs and chemicals.
Toxys
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Mitotox Assessment Xtension
ToxProfiler™ is a unique human in vitro assay that combines seven stable fluorescent reporter genes and can provide an extensive toxicological profile of novel drugs and chemicals.

Alternatives to Animal TestingNAM - New Approach Method
Clonogenic Survival Assay Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The clonogenic survival assay measures the effect of compounds on the proliferating ability of cells. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.
Toxys
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Price Upon Request

Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The clonogenic survival assay measures the effect of compounds on the proliferating ability of cells. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.

Alternatives to Animal Testing
ToxProfiler Mechanistic toxicity profiling. ToxProfilerTM is a unique New Approach Method (NAM) that provides an extensive and quantitative toxicological profile of novel pharmaceutical, (agro)chemical and cosmetic compounds.
Toxys
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Price Upon Request

Mechanistic toxicity profiling.
ToxProfilerTM is a unique New Approach Method (NAM) that provides an extensive and quantitative toxicological profile of novel pharmaceutical, (agro)chemical and cosmetic compounds.

Alternatives to Animal TestingNAM - New Approach Method
ReproTracker® Animal-free developmental toxicity predictions. ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.
Toxys
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Animal-free developmental toxicity predictions.
ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.

Alternatives to Animal Testing
In Vitro Comet Assay The comet assay can be used to detect DNA damage. We perform the comet assay in the ToxTracker cells, the DNA Repair-Profiler cell lines and other human cell lines.
Toxys
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The comet assay can be used to detect DNA damage. We perform the comet assay in the ToxTracker cells, the DNA Repair-Profiler cell lines and other human cell lines.

Alternatives to Animal Testing
Automated Micronucleus screening Automated Micronucleus screening The in vitro micronucleus test assesses induction of chromosomal damage upon chemical exposure. Micronuclei are cytoplasmic chromosomes or chromosome fragments that result from DNA strand breaks or incorrect chromosome segregation during cell division. The micronucleus test detects genotoxic substances with clastogenic and aneugenic activity.
Toxys
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Automated Micronucleus screening
The in vitro micronucleus test assesses induction of chromosomal damage upon chemical exposure. Micronuclei are cytoplasmic chromosomes or chromosome fragments that result from DNA strand breaks or incorrect chromosome segregation during cell division. The micronucleus test detects genotoxic substances with clastogenic and aneugenic activity.

Alternatives to Animal Testing
ReproTracker Service Animal-free developmental toxicity predictions ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.
Toxys
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Price Upon Request

Animal-free developmental toxicity predictions
ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.

Alternatives to Animal TestingNAM - New Approach Method
Hprt Mutation Assays DNA damage can lead to the induction of gene mutations. Mutagenesis is the driving force behind the development of various genetic diseases including cancer. Toxys has a longstanding experience in various mammalian gene mutation assays.
Toxys
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DNA damage can lead to the induction of gene mutations. Mutagenesis is the driving force behind the development of various genetic diseases including cancer. Toxys has a longstanding experience in various mammalian gene mutation assays.

Alternatives to Animal Testing
DNA Repair-Profiler Insights into DNA Repair and Genotoxicity. DNA Repair-Profiler consists of a unique collection of mammalian cell lines, each with a deficiency in one of the major DNA repair pathways.
Toxys
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Insights into DNA Repair and Genotoxicity.
DNA Repair-Profiler consists of a unique collection of mammalian cell lines, each with a deficiency in one of the major DNA repair pathways.

Alternatives to Animal Testing
AlveoliX
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Price Upon Request

Following your inspiration, we design and develop new models combining your expertise and our know-how. The custom model is first established and tested by our team and subsequently transferred to your lab. Our team will then provide support with your organs-on-chip experiments.

Alternatives to Animal Testing
AlveoliX
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Price Upon Request

Our efficacy models predict the effect of potential drug candidates in preclinical phases, allow to identify new therapeutic targets, and can be applied for personalized medicine approaches.

Alternatives to Animal Testing
AlveoliX
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By tuning cellular complexity, our toxicity models allow to identify cell-specific adverse-effects.

Alternatives to Animal Testing
Alcyomics
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Price Upon Request

Preclinical safety and efficacy testing of drugs as “first in man studies”, sensitisation testing of chemicals and cosmetics, safety and efficacy testing of cellular therapies. Human in vitro tests as alternative to animal models

Alternatives to Animal Testing
SCREENflex Stable Recombinant Cell Line Service Customised mammalian stable cell lines (CHO, HEK293 or custom cells) with stable and homogenous expression of your target.
InSCREENeX
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Per Day (EUR 1,000 to 3,000)
Project-based
Price Upon Request

Customised mammalian stable cell lines (CHO, HEK293 or custom cells) with stable and homogenous expression of your target.

Alternatives to Animal Testing
BeCytes Biotechnologies
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Project-based (GBP 10,000 to 1,250,000)

We manage a wide variety of services associated with research studies.

Alternatives to Animal Testing
MatTek
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Price Upon Request

The EpiAirway in vitro tissue model is used to determine the IC-75 value (concentration required to reduce tissue viability to 75% of vehicle control-treated tissues) of a test chemical.

Alternatives to Animal Testing