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Company - Toxys : Lab Services | A2A
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Toxys
Toxys
Netherlands
Toxys is a global leading expert that develops and offers a broad spectrum of unique animal-free laboratory tests for the safety assessment of novel medicines, chemicals, cosmetics and food.
We are experts in the fields of genotoxicity, developmental toxicology and mechanistic toxicity testing. We develop assays with the focus on understanding the mode-of-action of toxic compounds
Biotechnology Research
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Laboratory services
5 Products
1 Brand
15 Lab Services
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Alamar Blue Assay
Toxys
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Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The Alamar blue assay provides a rapid and sensitive quantitative analysis on cell proliferation and apoptosis. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.
Alternatives to Animal Testing
ToxProfiler MAX
Toxys
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Mitotox Assessment Xtension
ToxProfiler™ is a unique human in vitro assay that combines seven stable fluorescent reporter genes and can provide an extensive toxicological profile of novel drugs and chemicals.
Alternatives to Animal Testing
NAM - New Approach Method
Clonogenic Survival Assay
Toxys
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Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The clonogenic survival assay measures the effect of compounds on the proliferating ability of cells. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.
Alternatives to Animal Testing
ToxProfiler
Toxys
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Mechanistic toxicity profiling.
ToxProfilerTM is a unique New Approach Method (NAM) that provides an extensive and quantitative toxicological profile of novel pharmaceutical, (agro)chemical and cosmetic compounds.
Alternatives to Animal Testing
NAM - New Approach Method
ReproTracker®
Toxys
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Animal-free developmental toxicity predictions.
ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.
Alternatives to Animal Testing
In Vitro Comet Assay
Toxys
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The comet assay can be used to detect DNA damage. We perform the comet assay in the ToxTracker cells, the DNA Repair-Profiler cell lines and other human cell lines.
Alternatives to Animal Testing
Automated Micronucleus screening
Toxys
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Automated Micronucleus screening
The in vitro micronucleus test assesses induction of chromosomal damage upon chemical exposure. Micronuclei are cytoplasmic chromosomes or chromosome fragments that result from DNA strand breaks or incorrect chromosome segregation during cell division. The micronucleus test detects genotoxic substances with clastogenic and aneugenic activity.
Alternatives to Animal Testing
ReproTracker Service
Toxys
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Animal-free developmental toxicity predictions
ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.
Alternatives to Animal Testing
NAM - New Approach Method
Hprt Mutation Assays
Toxys
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DNA damage can lead to the induction of gene mutations. Mutagenesis is the driving force behind the development of various genetic diseases including cancer. Toxys has a longstanding experience in various mammalian gene mutation assays.
Alternatives to Animal Testing
DNA Repair-Profiler
Toxys
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Insights into DNA Repair and Genotoxicity.
DNA Repair-Profiler consists of a unique collection of mammalian cell lines, each with a deficiency in one of the major DNA repair pathways.
Alternatives to Animal Testing
ToxProfiler Service
Toxys
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We perform ToxProfiler as a service for our clients. You can send your compounds and receive a full report within 2-3 weeks. It is also possible to request a ToxProfiler test via scientist.com. Are you interested in receiving a quote or do you have any questions? Please reach out!
Alternatives to Animal Testing
TubulinTracker Service
Toxys
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Toxys offers TubulinTracker as a service from our state-of-the-art laboratory in Leiden, the Netherlands. You can send your compounds and receive a full report, in most cases within 2-3 weeks.
Alternatives to Animal Testing
ToxTracker AO Service
Toxys
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We can perform ToxTracker AO for you at our state-of-the-art laboratory. You can then send your compounds and receive a full report, in most cases within 2 weeks.
Alternatives to Animal Testing
ToxTracker ACE Service
Toxys
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We can perform ToxTracker ACE for you at our state-of-the-art laboratory. You can then send your compounds and receive a full report, in most cases within 2 weeks.
Alternatives to Animal Testing
ToxTracker Service
Toxys
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ToxTracker is routinely performed at our state-of-the-art laboratory. You can send your compounds and receive a full report in most cases within 2-3 weeks.
Alternatives to Animal Testing
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