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Alamar Blue Assay Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The Alamar blue assay provides a rapid and sensitive quantitative analysis on cell proliferation and apoptosis. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.
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Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The Alamar blue assay provides a rapid and sensitive quantitative analysis on cell proliferation and apoptosis. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.

Alternatives to Animal Testing
ToxProfiler MAX Mitotox Assessment Xtension ToxProfiler™ is a unique human in vitro assay that combines seven stable fluorescent reporter genes and can provide an extensive toxicological profile of novel drugs and chemicals.
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Mitotox Assessment Xtension
ToxProfiler™ is a unique human in vitro assay that combines seven stable fluorescent reporter genes and can provide an extensive toxicological profile of novel drugs and chemicals.

Alternatives to Animal TestingNAM - New Approach Method
Clonogenic Survival Assay Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The clonogenic survival assay measures the effect of compounds on the proliferating ability of cells. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.
Toxys
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Toxys is routinely running various cytotoxicity assays, including cell survival by relative cell count, MTT and Alamar blue metabolic cell viability stains and the clonogenic cell survival assay. The clonogenic survival assay measures the effect of compounds on the proliferating ability of cells. Apoptosis is assessed by flow cytometric analysis of caspase activity, Annexin V staining or TUNEL assay.

Alternatives to Animal Testing
ToxProfiler Mechanistic toxicity profiling. ToxProfilerTM is a unique New Approach Method (NAM) that provides an extensive and quantitative toxicological profile of novel pharmaceutical, (agro)chemical and cosmetic compounds.
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Mechanistic toxicity profiling.
ToxProfilerTM is a unique New Approach Method (NAM) that provides an extensive and quantitative toxicological profile of novel pharmaceutical, (agro)chemical and cosmetic compounds.

Alternatives to Animal TestingNAM - New Approach Method
ReproTracker® Animal-free developmental toxicity predictions. ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.
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Animal-free developmental toxicity predictions.
ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.

Alternatives to Animal Testing
In Vitro Comet Assay The comet assay can be used to detect DNA damage. We perform the comet assay in the ToxTracker cells, the DNA Repair-Profiler cell lines and other human cell lines.
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The comet assay can be used to detect DNA damage. We perform the comet assay in the ToxTracker cells, the DNA Repair-Profiler cell lines and other human cell lines.

Alternatives to Animal Testing
Automated Micronucleus screening Automated Micronucleus screening The in vitro micronucleus test assesses induction of chromosomal damage upon chemical exposure. Micronuclei are cytoplasmic chromosomes or chromosome fragments that result from DNA strand breaks or incorrect chromosome segregation during cell division. The micronucleus test detects genotoxic substances with clastogenic and aneugenic activity.
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Automated Micronucleus screening
The in vitro micronucleus test assesses induction of chromosomal damage upon chemical exposure. Micronuclei are cytoplasmic chromosomes or chromosome fragments that result from DNA strand breaks or incorrect chromosome segregation during cell division. The micronucleus test detects genotoxic substances with clastogenic and aneugenic activity.

Alternatives to Animal Testing
ReproTracker Service Animal-free developmental toxicity predictions ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.
Toxys
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Animal-free developmental toxicity predictions
ReproTracker® is a state-of-the-art human stem cell-based in vitro assay that rapidly and reliably identifies developmental toxicity hazards of new drugs and chemicals. The assay captures the key cellular events of stem cell differentiation and early embryonic development.

Alternatives to Animal TestingNAM - New Approach Method
Hprt Mutation Assays DNA damage can lead to the induction of gene mutations. Mutagenesis is the driving force behind the development of various genetic diseases including cancer. Toxys has a longstanding experience in various mammalian gene mutation assays.
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DNA damage can lead to the induction of gene mutations. Mutagenesis is the driving force behind the development of various genetic diseases including cancer. Toxys has a longstanding experience in various mammalian gene mutation assays.

Alternatives to Animal Testing
DNA Repair-Profiler Insights into DNA Repair and Genotoxicity. DNA Repair-Profiler consists of a unique collection of mammalian cell lines, each with a deficiency in one of the major DNA repair pathways.
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Insights into DNA Repair and Genotoxicity.
DNA Repair-Profiler consists of a unique collection of mammalian cell lines, each with a deficiency in one of the major DNA repair pathways.

Alternatives to Animal Testing
ToxProfiler Service We perform ToxProfiler as a service for our clients. You can send your compounds and receive a full report within 2-3 weeks. It is also possible to request a ToxProfiler test via scientist.com. Are you interested in receiving a quote or do you have any questions? Please reach out!
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We perform ToxProfiler as a service for our clients. You can send your compounds and receive a full report within 2-3 weeks. It is also possible to request a ToxProfiler test via scientist.com. Are you interested in receiving a quote or do you have any questions? Please reach out!

Alternatives to Animal Testing
TubulinTracker Service Toxys offers TubulinTracker as a service from our state-of-the-art laboratory in Leiden, the Netherlands. You can send your compounds and receive a full report, in most cases within 2-3 weeks.
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Toxys offers TubulinTracker as a service from our state-of-the-art laboratory in Leiden, the Netherlands. You can send your compounds and receive a full report, in most cases within 2-3 weeks.

Alternatives to Animal Testing
ToxTracker AO Service We can perform ToxTracker AO for you at our state-of-the-art laboratory. You can then send your compounds and receive a full report, in most cases within 2 weeks.
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We can perform ToxTracker AO for you at our state-of-the-art laboratory. You can then send your compounds and receive a full report, in most cases within 2 weeks.

Alternatives to Animal Testing
ToxTracker ACE Service We can perform ToxTracker ACE for you at our state-of-the-art laboratory. You can then send your compounds and receive a full report, in most cases within 2 weeks.
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We can perform ToxTracker ACE for you at our state-of-the-art laboratory. You can then send your compounds and receive a full report, in most cases within 2 weeks.

Alternatives to Animal Testing
ToxTracker Service ToxTracker is routinely performed at our state-of-the-art laboratory. You can send your compounds and receive a full report in most cases within 2-3 weeks.
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ToxTracker is routinely performed at our state-of-the-art laboratory. You can send your compounds and receive a full report in most cases within 2-3 weeks.

Alternatives to Animal Testing
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