Not tested on animals or is not used for testing on animals
Short Description The ToxTracker assay is a state-of-the-art stem cell-based reporter assay that provides mechanistic insight into genotoxic properties of compounds. ToxTracker AO (Antioxidant) is an extended version of the ToxTracker assay and includes discrimination between direct DNA reactivity of a compound and indirect genotoxicity caused by high levels of oxidative stress and the production of reactive oxygen species (ROS).
Target Application(s) / Sector(s) / Disease(s) Follow-up of a positive ToxTracker test, Follow-up of a positive in vitro micronucleus test, Genotoxicity testing of compounds when oxidative stress is the expected mode-of-action
